⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1416552 | 0.79 | POLB (0.44) | — | |
| SCHEMBL14067812 | 0.77 | CHRNB2 (0.46) | — | |
| SCHEMBL7263711 | 0.77 | — | — | |
| SCHEMBL27207846 | 0.77 | — | — | |
| SCHEMBL1416553 | 0.77 | — | — | |
| SCHEMBL8050961 | 0.77 | — | — | |
| SCHEMBL28598213 | 0.76 | ALOX15 (0.48) | — | |
| SCHEMBL13494788 | 0.76 | KDM4E (0.40) | — | |
| SCHEMBL15315487 | 0.75 | LMNA (0.56) | — | |
| SCHEMBL14559816 | 0.75 | POLB (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813302-A | Substituted tetrahydrofuran-2-carboxamides as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-2010185-B1 | DIHYDROTHIENOPYRIMIDINE FOR TREATING INFLAMMATORY DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2012-06-13 | — | — | EP | disclosed |