Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL3412782 | 0.92 | ALDH1A1 (0.74) | ALDH1A1CA1CA2CA9MAPK1 | |
| Quinoline SCHEMBL28635379 | 0.88 | ALDH1A1 (0.68) | ALDH1A1CA1CA2CA9MAPK1 | |
| Quinoline SCHEMBL9374715 | 0.88 | ALDH1A1 (0.68) | ALDH1A1HTTKDM4ECASP1SMN1; SMN2 | |
| Quinoline SCHEMBL2313500 | 0.85 | ALDH1A1 (0.85) | ALDH1A1HTTKDM4ECASP1SMN1; SMN2 | |
| Quinoline SCHEMBL27422586 | 0.85 | ALDH1A1 (0.85) | ALDH1A1HTTKDM4ECASP1SMN1; SMN2 | |
| Quinoline SCHEMBL27834738 | 0.85 | ALDH1A1 (0.85) | ALDH1A1HTTKDM4ECASP1SMN1; SMN2 | |
| Quinoline SCHEMBL27367976 | 0.85 | ALDH1A1 (0.94) | ALDH1A1HTTKDM4ECASP1SMN1; SMN2 | |
| Quinoline SCHEMBL27764565 | 0.85 | ALDH1A1 (0.63) | ALDH1A1HTTKDM4ECASP1SMN1; SMN2 | |
| Quinoline SCHEMBL27774631 | 0.85 | ALDH1A1 (0.63) | ALDH1A1CA1CA2CA9MAPK1 | |
| Quinoline SCHEMBL21535 | 0.83 | ALDH1A1 (0.74) | ALDH1A1HTTKDM4ECASP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101888999-B | Pyridylmethyl-sulfonamide compounds | BASF SE | 2013-12-11 | — | — | CN | disclosed |
| US-8299262-B2 | Pyridylmethyl-sulfonamide compounds | BASF SE (DE) | 2012-10-30 | — | — | US | disclosed |
| US-8178540-B2 | Pyrimidylmethyl-sulfonamide compounds | BASF SE (DE) | 2012-05-15 | — | — | US | disclosed |
| EP-2066643-B1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2011-03-16 | — | — | EP | disclosed |
| EP-2262794-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDE | BASF SE (DE) | 2010-12-22 | — | — | EP | disclosed |
| US-20100317516-A1 | Sulfonamide Compounds And Their Use As Fungicide | BASF SE (DE) | 2010-12-16 | — | — | US | disclosed |
| US-20100249077-A1 | Pyridylmethyl-Sulfonamide Compounds | BASF SE (DE) | 2010-09-30 | — | — | US | disclosed |
| EP-2231605-A1 | PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS | BASF SE (DE) | 2010-09-29 | — | — | EP | disclosed |
| EP-2069306-B1 | QUINOLINYLMETHYL COMPOUNDS | BASF SE (DE) | 2010-05-12 | — | — | EP | disclosed |
| US-20100077512-A1 | Pyridazin-4-ylmethyl-sulfonamides used as Fungicides and Against Arthropods | BASF SE (DE) | 2010-03-25 | — | — | US | disclosed |
| US-20090280982-A1 | Quinolinylmethyl Compounds | BASF SE (DE) | 2009-11-12 | — | — | US | disclosed |
| WO-2009103650-A1 | SULFONAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDE | BASF SE (DE) | 2009-08-27 | — | — | WO | disclosed |
| EP-2069306-A1 | QUINOLINYLMETHYL COMPOUNDS | BASF SE (DE) | 2009-06-17 | — | — | EP | disclosed |
| WO-2009071449-A1 | PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS | BASF SE (DE) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009071448-A1 | PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS | BASF SE (DE) | 2009-06-11 | — | — | WO | disclosed |
| EP-2066643-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-10 | — | — | EP | disclosed |
| EP-2064190-A1 | PYRIMIDYLMETHYL-SULFONAMIDE COMPOUNDS USEFUL AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008062011-A1 | PYRIMIDYLMETHYL-SULFONAMIDE COMPOUNDS USEFUL AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008062012-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008031824-A1 | QUINOLINYLMETHYL COMPOUNDS | BASF SE (DE) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317516-A1 | Sulfonamide Compounds And Their Use As Fungicide | STS, ARSA, CYP4X1 | ALDH1A1 887/4885CA1 2046/4885CA2 1900/4885 |
| US-20090280982-A1 | Quinolinylmethyl Compounds | CBR3, C1S, C5 | ALDH1A1 1812/4885CA1 2385/4885CA2 540/4885 |
| US-20100077512-A1 | Pyridazin-4-ylmethyl-sulfonamides used as Fungicides and Against Arthropods | PIR, PRDX4, PRDX2 | ALDH1A1 2607/4885CA1 3207/4885CA2 579/4885 |
| US-20100249077-A1 | Pyridylmethyl-Sulfonamide Compounds | CBR3, CBR1, CBS | ALDH1A1 1178/4885CA1 1970/4885CA2 564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.