Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | DUT | P33316 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4917240 | 1.00 | KIF11 (0.53) | KIF11TK1ALOX15NR2E1KCNH2 | |
| SCHEMBL2111572 | 0.88 | KIF11 (0.50) | KIF11TK1ALOX15CTSKTSHR | |
| SCHEMBL27081312 | 0.88 | KIF11 (0.50) | KIF11TK1KCNH2 | |
| SCHEMBL16472146 | 0.88 | KIF11 (0.50) | KIF11TK1KCNH2 | |
| SCHEMBL16009182 | 0.86 | KIF11 (0.55) | KIF11TK1ALOX15KCNH2CTSK | |
| SCHEMBL2131419 | 0.86 | KIF11 (0.55) | KIF11TK1ALOX15KCNH2CTSK | |
| SCHEMBL465454 | 0.83 | TK1 (0.46) | KIF11TK1ALOX15CTSKTSHR | |
| SCHEMBL6522822 | 0.83 | TK1 (0.46) | KIF11TK1ALOX15CTSKTSHR | |
| SCHEMBL4924705 | 0.82 | KIF11 (0.59) | KIF11TK1ALOX15NR2E1KCNH2 | |
| SCHEMBL4931427 | 0.82 | KIF11 (0.59) | KIF11TK1ALOX15NR2E1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7390825-B1 | Process for the preparation of oxazolidinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2008-06-24 | — | — | US | disclosed |
| US-20080146458-A1 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2008-06-19 | — | — | US | disclosed |
| US-20070265451-A1 | Process for the preparation of oxazolidinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070265451-A1 | Process for the preparation of oxazolidinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265451-A1 | Process for the preparation of oxazolidinones and method of use thereof | OXA1L, OTC, ODC1 | KIF11 3787/4885TK1 2805/4885ALOX15 1542/4885 |
| US-20080146458-A1 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | OXA1L, OGFOD1, CYP51A1 | KIF11 2957/4885TK1 2642/4885ALOX15 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.