Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681159 | 0.82 | NPC1 (0.58) | CYP3A4HSD17B10CES2CES1L3MBTL1 | |
| SCHEMBL8821906 | 0.81 | LTA4H (0.56) | LTA4HKMT2AMEN1TAAR1SLC6A9 | |
| Hydrochloric Acid SCHEMBL11489832 | 0.79 | LTA4H (0.55) | LTA4HCYP3A4KMT2AMEN1TAAR1 | |
| SCHEMBL4470958 | 0.79 | LTA4H (0.55) | LTA4HCYP3A4KMT2AMEN1TAAR1 | |
| SCHEMBL17483917 | 0.79 | NPC1 (0.50) | CES2CES1L3MBTL1NPC1PTGS2 | |
| Bromide SCHEMBL2795481 | 0.78 | LTA4H (0.53) | LTA4HCYP3A4KMT2AMEN1TAAR1 | |
| Hydrochloric Acid SCHEMBL4469144 | 0.78 | LTA4H (0.53) | LTA4HCYP3A4KMT2AMEN1TAAR1 | |
| SCHEMBL16162796 | 0.77 | ALDH1A1 (0.55) | CYP1A2CYP3A4KMT2AMEN1SLC6A9 | |
| SCHEMBL16162350 | 0.77 | ALDH1A1 (0.55) | CYP1A2CYP3A4KMT2AMEN1SLC6A9 | |
| SCHEMBL16171185 | 0.77 | LMNA (0.48) | CYP3A4L3MBTL1AKR1C3AKR1C2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139596-A1 | Modulators of Hcv Replication | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139596-A1 | Modulators of Hcv Replication | EIF2AK2, MAVS, IRF3 | LTA4H 3945/4885CYP1A2 3321/4885CYP3A4 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.