SCHEMBL14174342

SCHEMBL14174342

C=C(C)C(=O)OC(COc1ccccc1)COc1ccc(Cc2ccc(OCC(COc3ccccc3)OC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 3/20 0.43
MTNR1B P49286 3/20 0.43
SRD5A2 P31213 1/20 0.42
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
LMNA P02545 2/20 0.41
ELANE P08246 1/20 0.40
AR P10275 1/20 0.40
LTA4H P09960 3/20 0.40
PPARG P37231 3/20 0.40
PPARA Q07869 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19944470 0.97 LMNA (0.43) LMNALTA4HPPARGPPARA
SCHEMBL19944372 0.92 MTNR1A (0.50) MTNR1AMTNR1BPOLBMAPTLMNA
SCHEMBL9926765 0.89 AR (0.45) POLBMAPTLMNAELANEAR
SCHEMBL19944473 0.89 LTA4H (0.47) MTNR1AMTNR1BPOLBMAPTLMNA
SCHEMBL4197201 0.89 MAPT (0.47) MTNR1AMTNR1BPOLBMAPTLMNA
SCHEMBL6883461 0.86 PPARG (0.53) MTNR1AMTNR1BLMNAARPPARG
SCHEMBL17036919 0.86 POLB (0.46) MTNR1AMTNR1BPOLBMAPTAR
SCHEMBL4188595 0.86 MAPT (0.50) MTNR1AMTNR1BMAPTLMNAELANE
SCHEMBL11957216 0.86 MTNR1A (0.46) MTNR1AMTNR1BPOLBLMNA
SCHEMBL6880397 0.86 MTNR1A (0.46) MTNR1AMTNR1BPOLBMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8344076-B2 Prepared by the reaction of an epoxy compound and a reactive ester; adhesive DESIGNER MOLECULES, INC. (US) 2013-01-01 US disclosed
US-8344076-B2 Prepared by the reaction of an epoxy compound and a reactive ester; adhesive DESIGNER MOLECULES, INC. (US) 2013-01-01 US disclosed
US-20080142158-A1 HYDROLYTICALLY RESISTANT THERMOSET MONOMERS DESIGNER MOLECULES, INC. 2008-06-19 US disclosed
US-20080142158-A1 HYDROLYTICALLY RESISTANT THERMOSET MONOMERS DESIGNER MOLECULES, INC. 2008-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080142158-A1 HYDROLYTICALLY RESISTANT THERMOSET MONOMERS ESD, JMJD7, PCNA MTNR1A 2704/4885MTNR1B 1931/4885SRD5A2 2680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.