Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16443881 | 0.86 | ALOX15 (0.35) | GAA | |
| SCHEMBL27078172 | 0.81 | — | — | |
| SCHEMBL14119498 | 0.81 | — | — | |
| SCHEMBL23042973 | 0.81 | — | — | |
| SCHEMBL29235353 | 0.76 | ADRB2 (0.53) | — | |
| SCHEMBL20261156 | 0.76 | ADRB2 (0.53) | — | |
| SCHEMBL4420207 | 0.75 | MAPK1 (0.32) | — | |
| SCHEMBL16699682 | 0.75 | LMNA (0.36) | — | |
| SCHEMBL27077954 | 0.75 | DUT (0.34) | — | |
| SCHEMBL27078101 | 0.75 | DUT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388002-B2 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-06-17 | — | — | US | disclosed |