Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | POLG | P54098 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AHCY | P23526 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5080083 | 0.91 | FDPS (0.37) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL5086022 | 0.89 | ABCB11 (0.44) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL5083007 | 0.73 | ADORA2A (0.47) | AHCY | |
| SCHEMBL14175392 | 0.70 | ABCB11 (0.42) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL14175385 | 0.68 | ADORA2A (0.51) | — | |
| SCHEMBL5082995 | 0.68 | ADORA2A (0.46) | AHCY | |
| SCHEMBL22411463 | 0.68 | CDK2 (0.36) | POLB | |
| SCHEMBL12843976 | 0.67 | ADORA2A (0.44) | — | |
| SCHEMBL14175339 | 0.67 | PRKCA (0.36) | POLBGAANPSR1 | |
| SCHEMBL14175407 | 0.65 | FGFR1 (0.35) | ABCB11POLA1POLGFAPSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388002-B2 | Nucleosides, preparation thereof and use as inhibitors of RNA viral polymerases | BIOCRYST PHARMACEUTICALS, INC. (US) | 2008-06-17 | — | — | US | disclosed |