SCHEMBL14176752

SCHEMBL14176752

Cc1cc(C(=O)O)c(-c2c3ccc(=N)cc-3oc3cc(N)ccc23)cc1C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.62
USP2 O75604 4/20 0.60
ATM Q13315 2/20 0.60
CFTR P13569 1/20 0.60
PAX8 Q06710 1/20 0.60
GOPC Q9HD26 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.55
POLB P06746 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALPL P05186 1/20 0.41
ALPI P09923 1/20 0.41
ALPG P10696 1/20 0.41
DNASE1L3 Q13609 1/20 0.38
PRMT1 Q99873 1/20 0.38
CA9 Q16790 11/20 0.38
CA1 P00915 9/20 0.38
CA12 O43570 3/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14399196 0.92 ABCB1 (0.58) ABCB1USP2ATMCFTRPAX8
SCHEMBL12307302 0.89 ABCB1 (0.65) ABCB1USP2ATMCFTRPAX8
SCHEMBL17695458 0.88 ABCB1 (0.61) ABCB1USP2ATMCFTRPAX8
SCHEMBL14627720 0.86 ABCB1 (0.63) ABCB1USP2ATMCFTRPAX8
SCHEMBL29483446 0.86 ABCB1 (0.63) ABCB1USP2ATMCFTRPAX8
SCHEMBL13805717 0.85 MEN1 (0.46) ABCB1USP2ATMCFTRPAX8
SCHEMBL12716297 0.85 ABCB1 (0.63) ABCB1USP2ATMCFTRPAX8
SCHEMBL10082964 0.85 ABCB1 (0.59) ABCB1USP2ATMCFTRPAX8
SCHEMBL458205 0.84 ABCB1 (0.77) ABCB1USP2ATMCFTRPAX8
SCHEMBL23378600 0.84 ABCB1 (0.64) ABCB1USP2ATMCFTRPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080138817-A1 Novel Functional Peptide Nucleic Acid Monomer and Process for Producing the Same CREDIA JAPAN CO., LTD. (JP) 2008-06-12 US disclosed
US-7282575-B2 Functional peptide nucleic acid monomer and process for producing the same CREDIA JAPAN CO., LTD. (JP) 2007-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138817-A1 Novel Functional Peptide Nucleic Acid Monomer and Process for Producing the Same NSUN3, RNGTT, NSUN2 ABCB1 3974/4885USP2 2830/4885ATM 2320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.