Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14176881 | 0.97 | HSD11B1 (0.44) | HSD11B1KDM4EL3MBTL1TRPA1TRPV1 | |
| SCHEMBL2258896 | 0.87 | KDM4E (0.49) | HSD11B1KDM4EMALT1 | |
| SCHEMBL2256062 | 0.87 | MEN1 (0.52) | KDM4EL3MBTL1MEN1KMT2AHSD17B10 | |
| SCHEMBL2260184 | 0.85 | KDM4E (0.55) | KDM4EMEN1KMT2AGAAHSD17B10 | |
| SCHEMBL2257488 | 0.84 | MEN1 (0.46) | HSD11B1KDM4EMALT1MEN1KMT2A | |
| SCHEMBL14176663 | 0.84 | ALDH1A1 (0.45) | HSD11B1KDM4EL3MBTL1TRPA1TRPV1 | |
| SCHEMBL2256424 | 0.82 | MAPT (0.45) | KDM4ETRPV1MEN1MAPTKMT2A | |
| SCHEMBL2259894 | 0.82 | ALDH1A1 (0.50) | KDM4EMEN1MAPTKMT2ANPSR1 | |
| SCHEMBL14176659 | 0.81 | ALDH1A1 (0.43) | KDM4EL3MBTL1TRPA1TRPV1MEN1 | |
| SCHEMBL2259974 | 0.81 | SLC6A7 (0.48) | KDM4EMEN1MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073825-A1 | LXR AND FXR MODULATORS | EXELIXIS, INC. (US) | 2008-06-19 | — | — | WO | disclosed |