Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14181983 | 0.80 | HDAC1 (0.46) | NAMPTKDM4EHDAC6MAPK1HDAC3 | |
| SCHEMBL16688448 | 0.80 | MAPK1 (0.55) | NAMPTKDM4EHDAC6MAPK1 | |
| SCHEMBL3698235 | 0.80 | MAPK1 (0.38) | KDM4EMAPK1NPC1RAB9A | |
| SCHEMBL18870447 | 0.79 | ROCK2 (0.36) | KDM4E | |
| SCHEMBL24742360 | 0.79 | CRBN (0.32) | KDM4E | |
| SCHEMBL17035833 | 0.79 | L3MBTL1 (0.52) | KDM4ENPC1RAB9A | |
| SCHEMBL13349240 | 0.79 | POLB (0.48) | NAMPTKDM4ENPC1RAB9A | |
| SCHEMBL15177514 | 0.78 | L3MBTL1 (0.54) | MAPK1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL18726788 | 0.78 | POLB (0.49) | NAMPTKDM4ENPC1RAB9A | |
| SCHEMBL10014111 | 0.78 | HCAR3 (0.52) | NAMPTKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113875-A1 | MOLECULAR DETECTION BY MATRIX FREE DESORPTION IONIZATION MASS SPECTROMETRY | VANDERBILT UNIVERSITY | 2008-05-15 | — | — | US | disclosed |
| US-20080113875-A1 | MOLECULAR DETECTION BY MATRIX FREE DESORPTION IONIZATION MASS SPECTROMETRY | VANDERBILT UNIVERSITY | 2008-05-15 | — | — | US | disclosed |