Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.45 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.45 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182847 | 0.95 | HDAC6 (0.47) | MAOAMAOBNHERF1NR2E3ABCB1 | |
| SCHEMBL14182728 | 0.91 | MAOB (0.57) | MAOAMAOBNR2E3MAPTSLC2A1 | |
| SCHEMBL14182716 | 0.90 | MAOA (0.54) | MAOAMAOBNR2E3MAPTSLC2A1 | |
| SCHEMBL14182699 | 0.90 | MAOA (0.56) | MAOAMAOBROCK2PRKD3MAP4K4 | |
| SCHEMBL14182737 | 0.90 | MAOA (0.54) | MAOAMAOBNR2E3MAPTSLC2A1 | |
| SCHEMBL14182718 | 0.89 | MAOA (0.57) | MAOAMAOBNR2E3SLC2A1KMT2A | |
| SCHEMBL14182729 | 0.89 | KCNQ2 (0.55) | MAOAMAOBMAPTABCB1KMT2A | |
| SCHEMBL14182768 | 0.89 | KCNQ2 (0.55) | MAOAMAOBMAPTABCB1KMT2A | |
| SCHEMBL14182712 | 0.89 | ALDH1A1 (0.47) | MAOAMAOBROCK2PRKD3CLK2 | |
| SCHEMBL14182846 | 0.87 | SLC2A1 (0.48) | MAOAMAOBNR2E3MAPTSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |