Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182737 | 0.92 | MAOA (0.54) | SLC2A1KMT2AMAPTMEN1GAA | |
| SCHEMBL14182716 | 0.92 | MAOA (0.54) | SLC2A1KMT2AMAPTMEN1GAA | |
| SCHEMBL14182848 | 0.91 | KMT2A (0.50) | SLC2A1HDAC6KMT2AMAPTMEN1 | |
| SCHEMBL14182847 | 0.91 | HDAC6 (0.47) | SLC2A1HDAC6NR2E3MAOAMAOB | |
| SCHEMBL14182907 | 0.90 | ROCK2 (0.46) | SLC2A1HDAC6MAPTMAOAMAOB | |
| SCHEMBL14182906 | 0.90 | GSK3A (0.52) | MAPKAPK2JAK2 | |
| SCHEMBL14183016 | 0.90 | KCNK3 (0.56) | SLC2A1HDAC6KMT2AMAPTMEN1 | |
| SCHEMBL14182902 | 0.90 | KCNK3 (0.56) | SLC2A1HDAC6KMT2AMAPTMEN1 | |
| SCHEMBL14182862 | 0.90 | PLAU (0.52) | KMT2AMAPTMEN1JAK1ITK | |
| SCHEMBL14182911 | 0.88 | VCP (0.51) | SLC2A1HDAC6KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |