Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 9/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14183004 | 0.89 | GRM4 (0.53) | KDRGRM4HDAC6NPC1RAB9A | |
| SCHEMBL14182798 | 0.87 | GRM4 (0.48) | KDRGRM4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14182790 | 0.87 | SMN1; SMN2 (0.52) | GRM4NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14182795 | 0.87 | GRM4 (0.48) | KDRGRM4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14182802 | 0.85 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14182810 | 0.84 | RAB9A (0.40) | KDRGRM4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14182799 | 0.84 | GRM4 (0.40) | KDRGRM4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14182796 | 0.84 | RAB9A (0.44) | KDRGRM4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14183006 | 0.81 | GRM4 (0.59) | KDRGRM4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14183007 | 0.81 | GRM4 (0.59) | KDRGRM4NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |