Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 6/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14183005 | 0.90 | GRM4 (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL14183012 | 0.90 | GRM4 (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL14182799 | 0.89 | GRM4 (0.40) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL14182790 | 0.88 | SMN1; SMN2 (0.52) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL14182811 | 0.85 | CNR1 (0.41) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14182794 | 0.84 | KDR (0.46) | RAB9ANPC1SMN1; SMN2KDM4EGRM4 | |
| SCHEMBL14182638 | 0.83 | GRM4 (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL14182698 | 0.83 | GRM4 (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL14183010 | 0.83 | ITK (0.45) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL14182806 | 0.83 | ITK (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |