Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | ITK | Q08881 | 5/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182791 | 0.94 | ITK (0.48) | ITKSLC2A1MAOAMAOBRAB9A | |
| SCHEMBL14182806 | 0.94 | ITK (0.44) | CNR1CNR2ITKSLC2A1GAA | |
| SCHEMBL14183010 | 0.90 | ITK (0.45) | CNR1CNR2ITKSLC2A1GAA | |
| SCHEMBL14182807 | 0.86 | ALDH1A1 (0.41) | CNR2ITKRAB9ALMNAALDH1A1 | |
| SCHEMBL14182799 | 0.85 | GRM4 (0.40) | RAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL14182810 | 0.85 | RAB9A (0.40) | CNR1CNR2ITKSLC2A1RAB9A | |
| SCHEMBL14182996 | 0.85 | ITK (0.52) | ITKSLC2A1MAOAMAOBRAB9A | |
| SCHEMBL14183009 | 0.85 | ITK (0.52) | ITKSLC2A1MAOAMAOBRAB9A | |
| SCHEMBL14182789 | 0.82 | ITK (0.51) | ITKSLC2A1MAOAMAOBRAB9A | |
| SCHEMBL14182788 | 0.82 | ITK (0.51) | ITKSLC2A1MAOAMAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |