Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044211 | 0.83 | HTT (0.44) | KDM4EALDH1A1HTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL14183098 | 0.79 | ALDH1A1 (0.61) | GAAALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28757745 | 0.75 | HDAC1 (0.46) | GAAALDH1A1HTTL3MBTL1MEN1 | |
| SCHEMBL14183099 | 0.73 | HTR1D (0.41) | GAAMAPTHTR1D | |
| SCHEMBL23927516 | 0.72 | QDPR (0.45) | HTR1DHDAC2 | |
| SCHEMBL14183095 | 0.72 | TDP1 (0.41) | ALDH1A1MAPTHTR1D | |
| SCHEMBL3713654 | 0.71 | HDAC1 (0.44) | ALDH1A1HTTL3MBTL1MEN1KMT2A | |
| SCHEMBL5528760 | 0.70 | ALDH1A1 (0.68) | GAAKDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL32670809 | 0.70 | ALDH1A1 (0.68) | GAAKDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL17374756 | 0.69 | ALDH1A1 (0.41) | ALDH1A1HTR1DHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108826-A1 | PREPARATION OF 4-ALKOXY-7-(TETRAHYDRO-PYRAN-4-YL)-BENZOTHIAZOL-2-YLAMINE DERIVATIVES | HOFFMANN-LA ROCHE INC. | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108826-A1 | PREPARATION OF 4-ALKOXY-7-(TETRAHYDRO-PYRAN-4-YL)-BENZOTHIAZOL-2-YLAMINE DERIVATIVES | HTR7, HTR4, BRD7 | GAA 3536/4885KDM4E 214/4885ALDH1A1 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.