SCHEMBL14189059

SCHEMBL14189059

O=S(=O)(NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)c1nccs1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.43
CA2 P00918 8/20 0.43
SLC40A1 Q9NP59 1/20 0.40
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
MMP13 P45452 1/20 0.37
NLRP3 Q96P20 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KAT8 Q9H7Z6 1/20 0.35
BRAF P15056 1/20 0.33
ABCC9 O60706 1/20 0.33
ABCC8 Q09428 1/20 0.33
KCNJ11 Q14654 1/20 0.33
KCNJ8 Q15842 1/20 0.33
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18710026 0.74 SLC40A1 (0.46) CA1CA2SLC40A1NLRP3MEN1
SCHEMBL2347469 0.73 CA1 (0.71) CA1CA2MMP1MMP2MMP9
SCHEMBL14189054 0.72 SLC40A1 (0.31) SLC40A1MEN1KMT2A
SCHEMBL14189055 0.71 SCN1A (0.33) SLC40A1KAT8ABCC9ABCC8KCNJ11
SCHEMBL8229998 0.71 SLC40A1 (0.46) CA1CA2SLC40A1MMP1MMP2
SCHEMBL20308559 0.68 SLC40A1 (0.44) SLC40A1NLRP3MEN1KMT2AKAT8
SCHEMBL30817869 0.68
SCHEMBL502516 0.67 ABCC9 (0.44) SLC40A1NLRP3MEN1KMT2AABCC9
SCHEMBL1548657 0.67 SLC40A1 (0.43) SLC40A1NLRP3MEN1KMT2AABCC9
SCHEMBL28656315 0.66 MEN1 (0.32) SLC40A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378154-B2 Radiation transparent glass, polycarbonate, polyethylene terephthalate, acrylic, methyl cellulose or polycycloolefin substrate, a fluoropolymer layer containing and a rare earth metal compound, and a low refractive index layer; fluorescence; light amplification; improved efficiency; light emitting diodes DAIKIN INDUSTRIES, LTD. (JP) 2008-05-27 US disclosed
US-7378154-B2 Radiation transparent glass, polycarbonate, polyethylene terephthalate, acrylic, methyl cellulose or polycycloolefin substrate, a fluoropolymer layer containing and a rare earth metal compound, and a low refractive index layer; fluorescence; light amplification; improved efficiency; light emitting diodes DAIKIN INDUSTRIES, LTD. (JP) 2008-05-27 US disclosed
US-20070218289-A1 Photofunctional Laminated Article DAIKIN INDUSTRIES, LTD. (JP) 2007-09-20 US disclosed
US-20070218289-A1 Photofunctional Laminated Article DAIKIN INDUSTRIES, LTD. (JP) 2007-09-20 US disclosed
US-20070197718-A1 Photofunctional optical material comprising fluorine-containing acrylate polymer DAIKIN INDUSTRIES LTD. 2007-08-23 US disclosed