SCHEMBL28656315

SCHEMBL28656315

O=S(=O)(COc1c(F)c(F)c(F)c(F)c1F)c1nccs1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SLC40A1 Q9NP59 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28926012 0.91 PKM (0.36) MEN1KMT2ANPC1RAB9A
SCHEMBL28642467 0.72 PSEN1 (0.31)
SCHEMBL28642462 0.72
SCHEMBL8797268 0.71 FBP1 (0.38) SLC40A1
SCHEMBL28637870 0.70 HSD11B1 (0.40)
SCHEMBL8796833 0.68 NAMPT (0.32) SLC40A1
SCHEMBL3511229 0.67 CYP2C19 (0.40) SLC40A1
SCHEMBL30817869 0.67
SCHEMBL502516 0.66 ABCC9 (0.44) MEN1KMT2ASLC40A1
SCHEMBL14189059 0.66 CA1 (0.43) MEN1KMT2ASLC40A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113527224-B Thiazole derivative and application thereof in agriculture 宁夏苏融达化工有限公司 2023-07-04 CN disclosed
CN-113527224-A Thiazole derivative and application thereof in agriculture 宁夏苏融达化工有限公司 2021-10-22 CN disclosed