SCHEMBL14190959

SCHEMBL14190959

CC(C)(C)OC(=O)N1CCC(COc2ncc(Br)cc2[N+](=O)O)CC1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
GPR119 Q8TDV5 12/20 0.44
IDO1 P14902 1/20 0.42
TDO2 P48775 1/20 0.42
FAAH O00519 1/20 0.41
ALOX5AP P20292 1/20 0.41
FEN1 P39748 1/20 0.41
CHEK2 O96017 1/20 0.41
HDAC1 Q13547 1/20 0.40
KDM4E B2RXH2 1/20 0.40
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14285782 0.91 FNTA (0.43) FNTAFNTBGPR119IDO1TDO2
SCHEMBL16688920 0.85 GPR119 (0.46) FNTAFNTBGPR119IDO1TDO2
SCHEMBL16520051 0.83 SSTR4 (0.52) FNTAFNTBGPR119IDO1TDO2
SCHEMBL26590176 0.81 IDO1 (0.39) FNTAFNTBGPR119IDO1TDO2
SCHEMBL29968865 0.81 IDO1 (0.39) FNTAFNTBGPR119IDO1TDO2
SCHEMBL386491 0.80 GPR119 (0.50) FNTAFNTBGPR119IDO1TDO2
SCHEMBL17837669 0.78 GPR119 (0.48) FNTAFNTBGPR119IDO1TDO2
SCHEMBL29960962 0.78 GPR119 (0.50) FNTAFNTBGPR119IDO1TDO2
SCHEMBL28510099 0.78 GPR119 (0.50) FNTAFNTBGPR119IDO1TDO2
SCHEMBL15088038 0.77 IDO1 (0.47) FNTAFNTBGPR119IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080103123-A1 New compounds BIOVITRUM (SE) 2008-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080103123-A1 New compounds GPR119, GPR139, GPR180 FNTA 2175/4885FNTB 2886/4885GPR119 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.