Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PTAFR | P25105 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12154243 | 0.82 | L3MBTL1 (0.59) | L3MBTL1KMT2AMEN1MAPTPDGFRB | |
| SCHEMBL14192519 | 0.81 | ITGB3 (0.38) | MAPTBCHEGAACNR2 | |
| SCHEMBL14192498 | 0.80 | L3MBTL1 (0.46) | L3MBTL1KMT2AMEN1MAPTPDGFRB | |
| SCHEMBL20274052 | 0.76 | THRB (0.43) | KMT2AALDH1A1CYP3A4HPGDTSHR | |
| SCHEMBL24555329 | 0.76 | KMT2A (0.41) | KMT2AMEN1ALDH1A1HPGDF2 | |
| SCHEMBL18199239 | 0.74 | THRB (0.41) | KMT2AALDH1A1CYP3A4HPGDTSHR | |
| SCHEMBL20045170 | 0.74 | KMT2A (0.61) | L3MBTL1KMT2AMEN1MAPTHPGD | |
| SCHEMBL12154218 | 0.74 | KMT2A (0.61) | L3MBTL1KMT2AMEN1MAPTHPGD | |
| SCHEMBL8216786 | 0.73 | TP53 (0.50) | TSHRNPC1SMN1; SMN2 | |
| SCHEMBL9617785 | 0.73 | SMN1; SMN2 (0.46) | KMT2AMAPTALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |