Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192600 | 0.96 | MAPT (0.41) | MAPTNPC1RAB9AALDH5A1ABAT | |
| SCHEMBL14192598 | 0.90 | TDP2 (0.41) | MAPTNPC1RAB9AALDH5A1ABAT | |
| SCHEMBL14218951 | 0.88 | NPC1 (0.38) | MAPTNPC1RAB9AALDH5A1ABAT | |
| SCHEMBL14192491 | 0.86 | ACACB (0.45) | MAPTNPC1KDM4EMEN1ALDH1A1 | |
| SCHEMBL8836273 | 0.82 | MAPT (0.58) | MAPTNPC1RAB9AALDH5A1ABAT | |
| SCHEMBL14192454 | 0.82 | ALDH5A1 (0.61) | MAPTRAB9AALDH5A1ABATAKT1 | |
| SCHEMBL14192579 | 0.79 | ALDH5A1 (0.41) | MAPTALDH5A1ABATAKT1CYP3A4 | |
| SCHEMBL14192559 | 0.79 | MEN1 (0.56) | MAPTALDH5A1ABATAKT1CYP3A4 | |
| SCHEMBL14192593 | 0.77 | ALDH5A1 (0.41) | MAPTALDH5A1ABATAKT1CYP3A4 | |
| SCHEMBL14192590 | 0.75 | MEN1 (0.51) | MAPTALDH5A1ABATAKT1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |