Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 4/20 | 0.36 |
| ▸ | RARB | P10826 | 4/20 | 0.36 |
| ▸ | RARG | P13631 | 4/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192577 | 0.88 | MAPT (0.44) | NPC1MAPTRAB9ARARARARB | |
| SCHEMBL14192600 | 0.84 | MAPT (0.41) | NPC1MAPTRAB9ARARARARB | |
| SCHEMBL14192598 | 0.79 | TDP2 (0.41) | NPC1MAPTRAB9ARARARARB | |
| SCHEMBL14192491 | 0.77 | ACACB (0.45) | NPC1MAPTACACBKMT2A | |
| SCHEMBL8836273 | 0.72 | MAPT (0.58) | NPC1MAPTRAB9AALDH5A1ABAT | |
| SCHEMBL14192454 | 0.71 | ALDH5A1 (0.61) | MAPTRAB9ARARBRARGACACB | |
| SCHEMBL14192593 | 0.70 | ALDH5A1 (0.41) | MAPTRARARARBRARGALDH5A1 | |
| SCHEMBL14192579 | 0.70 | ALDH5A1 (0.41) | MAPTRARARARBRARGALDH5A1 | |
| SCHEMBL14192559 | 0.69 | MEN1 (0.56) | MAPTRARARARBRARGACACB | |
| SCHEMBL14192466 | 0.66 | ALDH5A1 (0.43) | MAPTRARARARBRARGACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |