Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 3/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192434 | 0.96 | KMT2A (0.39) | KMT2ATHRBTHRAMAPTALDH5A1 | |
| SCHEMBL14192443 | 0.83 | TMPRSS15 (0.40) | KMT2ATHRBGSTP1ROCK1MAPT | |
| SCHEMBL14192596 | 0.83 | MAPT (0.44) | KMT2ATHRBMAPTALDH5A1ABAT | |
| SCHEMBL13024945 | 0.83 | THRB (0.39) | KMT2ATHRBGSTP1THRAMAPT | |
| SCHEMBL13310809 | 0.83 | CHRNB2 (0.37) | KMT2ATHRBGSTP1THRAMAPT | |
| SCHEMBL14192469 | 0.80 | ALDH5A1 (0.46) | KMT2ATHRBTHRAMAPTALDH5A1 | |
| SCHEMBL14192470 | 0.80 | ALDH5A1 (0.46) | KMT2ATHRBTHRAMAPTALDH5A1 | |
| SCHEMBL14192477 | 0.80 | TDP1 (0.39) | KMT2ATHRBPPARGPPARDPPARA | |
| SCHEMBL12242636 | 0.79 | GSTP1 (0.36) | KMT2ATHRBGSTP1PPARGPPARD | |
| SCHEMBL14192546 | 0.79 | MAPT (0.48) | KMT2ATHRBTHRAMAPTALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |