SCHEMBL1419546

SCHEMBL1419546

c1ccc(-c2c3nc(c(-c4ccccc4)c4ccc([nH]4)c(-c4ccccc4)c4nc(c(-c5ccccc5)c5ccc2[nH]5)CC4)CC3)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.41
▸ STAT1 P42224 1/20 0.41
▸ NPC1 O15118 3/20 0.38
▸ RAB9A P51151 3/20 0.38
▸ ESR1 P03372 1/20 0.38
▸ ESR2 Q92731 1/20 0.38
▸ DYRK3 O43781 1/20 0.38
▸ CLK1 P49759 1/20 0.38
▸ CLK2 P49760 1/20 0.38
▸ CLK3 P49761 1/20 0.38
▸ GSK3B P49841 1/20 0.38
▸ CDK5 Q00535 1/20 0.38
▸ DYRK1A Q13627 1/20 0.38
▸ CDK5R1 Q15078 1/20 0.38
▸ DYRK2 Q92630 1/20 0.38
▸ CLK4 Q9HAZ1 1/20 0.38
▸ DYRK1B Q9Y463 1/20 0.38
▸ KDM4E B2RXH2 3/20 0.38
▸ ALDH1A1 P00352 3/20 0.38
▸ LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4413776 0.90 TOP1 (0.53) STAT3STAT1TOP1CYCS
SCHEMBL16270682 0.88 CYCS (0.54) STAT3STAT1TOP1CYCS
SCHEMBL7260971 0.87 MAPT (0.36) STAT3STAT1ESR1ESR2KDM4E
SCHEMBL8676967 0.82 STAT3 (0.46) STAT3STAT1TOP1CYCS
SCHEMBL19901985 0.82 TOP1 (0.60) STAT3STAT1TOP1CYCS
SCHEMBL19326350 0.82 TOP1 (0.49) STAT3STAT1TOP1CYCS
SCHEMBL2673225 0.80 STAT3 (0.50) STAT3STAT1NPC1RAB9AESR1
SCHEMBL16923752 0.79 TOP1 (0.46) STAT3STAT1TOP1CYCS
SCHEMBL17934754 0.79 TOP1 (0.75) STAT3STAT1KDM4EALDH1A1TOP1
SCHEMBL14181439 0.79 STAT3 (0.46) STAT3STAT1TOP1CYCS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3265120-B1 METHOD PCI BIOTECH AS (NO) 2023-07-05 — — EP claimed
US-11648287-B2 Composition for the treatment of intracellular bacterial infection ACADEMISCH MEDISCH CENTRUM (NL) 2023-05-16 — — US claimed
US-7157432-B2 Tetraphenylbacteriochlorin derivatives and compositions containing the same SAN-EI GEN F.F.I., INC. (JP) 2007-01-02 — — US claimed
US-20060003946-A1 Tissue-penetrating property, and exhibits high selectivity to tumor cells and hydrophilicity REI MEDICAL CO., LTD. (JP) 2006-01-05 — — US claimed
EP-1316558-B9 TETRAPHENYLBACTERIOCHLORIN DERIVATIVES AND COMPOSITIONS CONTAINING THE SAME SAN EI GEN FFI INC (JP) 2005-12-07 — — EP claimed
US-6958389-B2 Tetraphenylbacteriochlorin derivatives and compositions containing the same SAN-EI GEN F.F.I. INC. (JP) 2005-10-25 — — US claimed
EP-1316558-B1 TETRAPHENYLBACTERIOCHLORIN DERIVATIVES AND COMPOSITIONS CONTAINING THE SAME SAN EI GEN FFI INC (JP) 2005-08-17 — — EP claimed
US-20030171305-A1 Tetraphenylbacteriochlorin derivatives and compositions containing the same REI MEDICAL CO., LTD. (JP) 2003-09-11 — — US claimed
EP-1316558-A1 TETRAPHENYLBACTERIOCHLORIN DERIVATIVES AND COMPOSITIONS CONTAINING THE SAME SAN-EI GEN F.F.I., INC. (JP) 2003-06-04 — — EP claimed
US-20240115731-A1 METHOD OF DELIVERING MRNA IN VIVO PCI BIOTECH AS (NO) 2024-04-11 — — US disclosed
WO-2024068795-A1 METHOD FOR RELEASING VIRAL VECTORS PCI BIOTECH AS (NO) 2024-04-04 — — WO disclosed
EP-3743110-B1 MRNA MOLECULE AND PHOTOSENSITIZING AGENT FOR MEDICAL USE PCI BIOTECH AS (NO) 2024-01-10 — — EP disclosed
EP-4288065-A1 METHOD OF DELIVERING MRNA IN VIVO PCI Biotech AS (NO) 2023-12-13 — — EP disclosed
CN-116981464-A Methods for in vivo delivery of mRNA PCI生物技术有限公司 2023-10-31 — — CN disclosed
US-6420648-B1 SOLAR CELLS NORTH CAROLINA STATE UNIVERSITY 2002-07-16 — — US disclosed
US-6407330-B1 A CIRCUIT ELECTRICALLY COUPLED TO SAID SOLAR CELL; LIGHT HARVESTING RODS OF NON-DISCOTIC BACKBONE POLYMER CONTAINING CHROMOPHORE GROUPS NORTH CAROLINA STATE UNIVERSITY 2002-06-18 — — US disclosed
WO-2002020536-A1 TETRAPHENYLBACTERIOCHLORIN DERIVATIVES AND COMPOSITIONS CONTAINING THE SAME SAN-EI GEN F.F.I.,INC. (JP) 2002-03-14 — — WO disclosed
WO-2002009196-A1 LIGHT HARVESTING ARRAYS NORTH CAROLINA STATE UNIVERSITY (US) 2002-01-31 — — WO disclosed
WO-2002009197-A1 SOLAR CELLS INCORPORATING LIGHT HARVESTING ARRAYS NORTH CAROLINA STATE UNIVERSITY (US) 2002-01-31 — — WO disclosed
US-6123923-A ADMINISTERING A PATIENT A CONTRAST AGENT CONTAINING A STABILIZER, A PHOTOACTIVE AGENT, A GASEOUS PRECURSOR SUCH AS PERFLUORINATED COMPOUND OR GAS OR BOTH, AND SCANNING THE PATIENT USING ULTRASOUND IMAGING AND OPTICAL IMAGING IMARX PHARMACEUTICAL CORP. (US) 2000-09-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030171305-A1 Tetraphenylbacteriochlorin derivatives and compositions containing the same SCNN1B, SLC7A1, MGMT STAT3 2801/4885STAT1 2660/4885NPC1 4537/4885
US-20240115731-A1 METHOD OF DELIVERING MRNA IN VIVO NSUN2, LCP1, NSUN3 STAT3 240/4885STAT1 196/4885NPC1 908/4885
US-20060003946-A1 Tissue-penetrating property, and exhibits high selectivity to tumor cells and hydrophilicity CD68, SLC7A1, SLC11A2 STAT3 1848/4885STAT1 1190/4885NPC1 4200/4885
US-11648287-B2 Composition for the treatment of intracellular bacterial infection ACTB, NFATC1, IFNG STAT3 821/4885STAT1 359/4885NPC1 2749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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