Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | CYCS | P99999 | 3/20 | 0.51 |
| ▸ | TERT | O14746 | 4/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16270682 | 0.98 | CYCS (0.54) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL19901985 | 0.92 | TOP1 (0.60) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL8676967 | 0.92 | STAT3 (0.46) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL19326350 | 0.92 | TOP1 (0.49) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL1419546 | 0.90 | STAT3 (0.41) | TOP1STAT3STAT1CYCS | |
| SCHEMBL17934754 | 0.88 | TOP1 (0.75) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL16923752 | 0.88 | TOP1 (0.46) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL14181439 | 0.88 | STAT3 (0.46) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL29405434 | 0.88 | TOP1 (0.64) | TOP1STAT3STAT1CYCSTERT | |
| SCHEMBL30136 | 0.88 | TOP1 (0.64) | TOP1STAT3STAT1CYCSTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8096419-B2 | Compound | PCI BIOTECH AS (NO) | 2012-01-17 | — | — | US | disclosed |
| US-20110034325-A1 | HIGH PERFORMANCE ORR (OXYGEN REDUCTION REACTION) PGM (PT GROUP METAL) FREE CATALYST | ACTA S.P.A. (IT) | 2011-02-10 | — | — | US | disclosed |
| US-20100121255-A1 | COMPOUND | THE NORWEGIAN RADIUM HOSPITAL RESEARCH FOUNDATION (NO) | 2010-05-13 | — | — | US | disclosed |
| US-7662807-B2 | Sulphonated meso-tetraphenyl chlorins | THE NORWEGIAN RADIUM HOSPITAL RESEARCH FOUNDATION (NO) | 2010-02-16 | — | — | US | disclosed |
| EP-1472259-B1 | TETRAPYRROLIC MACROCYCLES AS PHOTODYNAMIC AGENTS | CIPAN COMP IND PROD (PT) | 2009-09-02 | — | — | EP | disclosed |
| US-7375215-B2 | tetrakis(hydroxyphenyl)chlorin, bacteriochlorin or isobacteriochlorin, derivatised at one or more of the hydroxy groups by addition reaction with a diisocyanate, diisothiocyanate or isocyanate; photodynamic therapy of cancerous and other diseased tissues | BIOSCIENCE TECHNOLOGY INVESTMENT HOLDINGS LIMITED (MY) | 2008-05-20 | — | — | US | disclosed |
| EP-1472259-A1 | TETRAPYRROLIC MACROCYCLES AS PHOTODYNAMIC AGENTS | CIPAN-Companhia Industrial Produtora De Antibioticos, S.A. (PT) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003064427-A1 | TETRAPYRROLIC MACROCYCLES AS PHOTODYNAMIC AGENTS | CIPAN - COMPANHIA INDUSTRIAL PRODUTORA DE ANTIBIOTICOS, S.A. (PT) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121255-A1 | COMPOUND | TPP2, TPP1, PTDSS2 | TOP1 2295/4885STAT3 3739/4885STAT1 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.