Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332380 | 0.78 | MAPT (0.62) | MAPTSMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL22096860 | 0.78 | MAPT (0.62) | MAPTSMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL14612751 | 0.78 | MAPT (0.62) | MAPTSMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL11417093 | 0.77 | MAPT (0.61) | MAPTSMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL10857157 | 0.77 | ALDH1A1 (0.42) | MAPTSMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL11521420 | 0.76 | MAPT (1.00) | MAPTSMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL11521418 | 0.76 | MAPT (1.00) | MAPTSMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL16472974 | 0.76 | MAPT (1.00) | MAPTSMN1; SMN2ALDH1A1HPGDALOX15 | |
| SCHEMBL28909818 | 0.75 | EGFR (0.49) | MAPTALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL27958960 | 0.75 | MAPT (0.54) | MAPTSMN1; SMN2ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096894-A1 | Anti-Bacterial Compounds | ASTON UNIVERSITY (GB) | 2008-04-24 | — | — | US | disclosed |
| US-20080096894-A1 | Anti-Bacterial Compounds | ASTON UNIVERSITY (GB) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096894-A1 | Anti-Bacterial Compounds | MRPL21, PGLS, FOSB | MAPT 2813/4885SMN1; SMN2 4485/4885ALDH1A1 3322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.