Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 8/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | PTAFR | P25105 | 9/20 | 0.55 |
| ▸ | FNTA | P49354 | 4/20 | 0.50 |
| ▸ | FNTB | P49356 | 4/20 | 0.50 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208366 | 0.86 | FNTA (0.65) | HRH1KCNH2CHRM2HTR1ACHRM1 | |
| SCHEMBL9832197 | 0.83 | PTAFR (0.76) | HRH1KCNH2CHRM2HTR1ACHRM1 | |
| Water SCHEMBL29400294 | 0.83 | PTAFR (0.51) | HRH1KCNH2PTAFRFNTAFNTB | |
| SCHEMBL9373907 | 0.75 | PTAFR (0.74) | HRH1PTAFRFNTAFNTBSLC6A15 | |
| Azatadine SCHEMBL3721 | 0.72 | HRH1 (1.00) | HRH1KCNH2CHRM2HTR1ACHRM1 | |
| Azatadine SCHEMBL29746602 | 0.72 | HRH1 (1.00) | HRH1KCNH2CHRM2HTR1ACHRM1 | |
| Azatadine SCHEMBL29363595 | 0.72 | HRH1 (1.00) | HRH1KCNH2CHRM2HTR1ACHRM1 | |
| SCHEMBL9208700 | 0.72 | SETD7 (0.71) | HRH1KCNH2CHRM2HTR1ACHRM1 | |
| SCHEMBL9207250 | 0.72 | HRH1 (0.75) | HRH1KCNH2PTAFRFNTAFNTB | |
| SCHEMBL14007275 | 0.71 | PTAFR (0.76) | HRH1KCNH2CHRM2HTR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7355042-B2 | Treatment of CNS disorders using CNS target modulators | HYPNION, INC. (US) | 2008-04-08 | — | — | US | disclosed |