Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 17/20 | 0.75 |
| ▸ | FNTA | P49354 | 3/20 | 0.60 |
| ▸ | FNTB | P49356 | 3/20 | 0.60 |
| ▸ | PTAFR | P25105 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136454 | 0.86 | HRH1 (1.00) | HRH1FNTAFNTBPTAFRKCNH2 | |
| SCHEMBL9208366 | 0.84 | FNTA (0.65) | HRH1FNTAFNTBPTAFRKCNH2 | |
| SCHEMBL9387368 | 0.83 | FNTA (0.82) | HRH1FNTAFNTBPTAFR | |
| SCHEMBL9214088 | 0.82 | FNTA (0.75) | HRH1FNTAFNTBPTAFR | |
| SCHEMBL6995933 | 0.80 | FNTA (0.77) | FNTAFNTB | |
| SCHEMBL6995930 | 0.80 | FNTA (0.77) | FNTAFNTB | |
| SCHEMBL6995938 | 0.79 | FNTA (0.57) | HRH1FNTAFNTB | |
| SCHEMBL9373907 | 0.79 | PTAFR (0.74) | HRH1FNTAFNTBPTAFR | |
| SCHEMBL6994690 | 0.79 | HRH1 (0.71) | HRH1FNTAFNTBPTAFRKCNH2 | |
| SCHEMBL7002988 | 0.78 | FNTA (0.60) | HRH1FNTAFNTBPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535152-B1 | Bis-benzo or benzopyrido cyclo hepta piperidene, piperidylene and piperazine compounds as PAF antagonists and compositions thereof. | SCHERING CORP (US) | 1995-08-09 | — | — | EP | disclosed |
| US-5422351-A | Antiallergens; antiinflammatory agents | SCHERING CORPORATION (US) | 1995-06-06 | — | — | US | disclosed |