Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 6/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727453 | 0.79 | NPC1 (0.51) | AHRKIF11KMT2AMAPTMEN1 | |
| SCHEMBL7836059 | 0.77 | AHR (0.54) | AHRKIF11KMT2AMAPTMEN1 | |
| SCHEMBL4625769 | 0.76 | KDM4E (0.51) | KMT2AMAPTTDP1NPSR1MITF | |
| SCHEMBL1557504 | 0.76 | KDM4E (0.55) | AHRKIF11KMT2AMAPTMEN1 | |
| SCHEMBL3151973 | 0.71 | NR4A2 (0.59) | KIF11KMT2AMAPTMEN1NPSR1 | |
| SCHEMBL14519076 | 0.70 | GSK3B (0.53) | AHRKIF11KMT2AMAPTMEN1 | |
| SCHEMBL4624897 | 0.70 | NR4A2 (0.44) | KIF11KMT2AMAPTNPSR1MITF | |
| SCHEMBL1093112 | 0.70 | CDK1 (0.51) | AHRKIF11KMT2AMAPTMEN1 | |
| SCHEMBL29953709 | 0.70 | CDK1 (0.51) | AHRKIF11KMT2AMAPTMEN1 | |
| SCHEMBL5776615 | 0.69 | KDM4E (0.45) | KMT2AMAPTMEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097135-B1 | PROCESS FOR THE PREPARATION OF AN INDOLE DERIVATIVE | SMITHKLINE BEECHAM PLC (GB) | 2008-05-07 | — | — | EP | disclosed |