Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5775281 | 0.84 | KDM4E (0.48) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9264435 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL5812465 | 0.82 | ALOX15 (0.54) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9236381 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9573791 | 0.80 | TUBB4A (0.46) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL3198815 | 0.78 | ALOX15 (0.68) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL29744098 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1557504 | 0.75 | KDM4E (0.55) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL5774466 | 0.74 | ALOX15 (0.46) | MEN1KMT2AHPGDTSHRALOX15 | |
| Phosphine SCHEMBL23422273 | 0.74 | ALOX15 (0.66) | KDM4EALDH1A1MAPTRAB9ATUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472221-B1 | SUBSTITUTED INDOLES, METHOD FOR PRODUCTION AND USE THEREOF FOR THE INHIBITION OF PAIN | GRUENENTHAL GMBH (DE) | 2006-03-22 | — | — | EP | disclosed |