Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 4/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060607 | 0.91 | GGPS1 (0.51) | GGPS1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL14199572 | 0.87 | GGPS1 (0.53) | GGPS1LAP3ANPEPFDPS | |
| SCHEMBL12257840 | 0.84 | GGPS1 (0.55) | GGPS1SMN1; SMN2FDPS | |
| SCHEMBL14199553 | 0.78 | GGPS1 (0.75) | GGPS1LMNAHTTSMN1; SMN2FDPS | |
| SCHEMBL12060604 | 0.78 | GGPS1 (0.58) | GGPS1LMNALAP3ANPEPFDPS | |
| SCHEMBL14228034 | 0.77 | LMNA (0.43) | GGPS1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL12257810 | 0.76 | GGPS1 (0.58) | GGPS1SMN1; SMN2FDPS | |
| SCHEMBL12257842 | 0.75 | GGPS1 (0.57) | GGPS1SMN1; SMN2FDPS | |
| SCHEMBL14199558 | 0.75 | GGPS1 (0.42) | GGPS1FDPSACP3 | |
| SCHEMBL14199559 | 0.72 | GGPS1 (0.52) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358361-B2 | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-15 | — | — | US | disclosed |