Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 6/20 | 0.41 |
| ▸ | LAP3 | P28838 | 5/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.38 |
| ▸ | ACP3 | P15309 | 2/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060607 | 0.81 | GGPS1 (0.51) | LMNAANPEPLAP3FDPSERAP1 | |
| SCHEMBL14199554 | 0.77 | GGPS1 (0.47) | LMNAANPEPLAP3FDPSALDH1A1 | |
| Diphenylmethane SCHEMBL28898534 | 0.69 | CALM1 (0.67) | LMNAANPEPLAP3FDPSERAP1 | |
| SCHEMBL12060604 | 0.69 | GGPS1 (0.58) | LMNAANPEPLAP3FDPSGGPS1 | |
| SCHEMBL12060363 | 0.68 | FDPS (0.54) | LMNAFDPSALDH1A1SMN1; SMN2HTT | |
| SCHEMBL12048155 | 0.67 | FDPS (0.49) | LMNAFDPSALDH1A1SMN1; SMN2HTT | |
| SCHEMBL14199572 | 0.65 | GGPS1 (0.53) | ANPEPLAP3FDPSGGPS1 | |
| SCHEMBL13851328 | 0.65 | ALDH1A1 (0.53) | LMNAALDH1A1SMN1; SMN2HTTKDM4E | |
| Bromide SCHEMBL3361424 | 0.64 | ALDH1A1 (0.51) | LMNAALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL13934017 | 0.64 | CALM1 (0.57) | LMNAALDH1A1SMN1; SMN2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358361-B2 | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-15 | — | — | US | disclosed |