Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 11/20 | 0.37 |
| ▸ | FDPS | P14324 | 4/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060616 | 0.91 | GGPS1 (0.39) | GGPS1FDPSSRC | |
| SCHEMBL14199570 | 0.72 | GGPS1 (0.55) | GGPS1FDPS | |
| SCHEMBL14199554 | 0.69 | GGPS1 (0.47) | GGPS1FDPS | |
| Hydrochloric Acid SCHEMBL5671113 | 0.68 | GGPS1 (0.40) | GGPS1FDPSSRC | |
| SCHEMBL14199553 | 0.68 | GGPS1 (0.75) | GGPS1FDPS | |
| SCHEMBL14199562 | 0.67 | GGPS1 (0.51) | GGPS1FDPS | |
| SCHEMBL14199561 | 0.67 | GGPS1 (0.44) | GGPS1FDPS | |
| SCHEMBL12257840 | 0.67 | GGPS1 (0.55) | GGPS1FDPS | |
| SCHEMBL14199558 | 0.67 | GGPS1 (0.42) | GGPS1FDPS | |
| SCHEMBL14199572 | 0.66 | GGPS1 (0.53) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358361-B2 | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-15 | — | — | US | disclosed |