Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12401767 | 0.84 | ALDH1A1 (0.37) | ALDH1A1TSHRTDP1ALOX5APFEN1 | |
| SCHEMBL14405259 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1LMNAPTGS2 | |
| SCHEMBL10824246 | 0.76 | GABRA1 (0.37) | ALDH1A1TSHRTDP1GABRA1GABRB2 | |
| SCHEMBL19240338 | 0.76 | ALOX5AP (0.42) | ALDH1A1TSHRTDP1ALOX5APFEN1 | |
| SCHEMBL31588937 | 0.75 | ADRA2A (0.39) | ALDH1A1TSHRTDP1ALOX5APFEN1 | |
| SCHEMBL19194345 | 0.74 | MAPT (0.33) | ALDH1A1TSHRTDP1ALOX5APFEN1 | |
| SCHEMBL21567219 | 0.74 | L3MBTL1 (0.41) | ALDH1A1TSHRLMNAHPGDPTGS2 | |
| SCHEMBL20457053 | 0.74 | GABRA1 (0.35) | ALDH1A1TSHRTDP1GABRA1GABRB2 | |
| SCHEMBL16829382 | 0.73 | ALOX5AP (0.36) | ALDH1A1TSHRTDP1ALOX5APFEN1 | |
| SCHEMBL26030932 | 0.72 | GABRA1 (0.48) | ALDH1A1TSHRTDP1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778874-B2 | Glycopeptide antibiotic monomer derivatives | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | SHIONOGI & CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | CSGALNACT1, MON2, NR2C2 | ALDH1A1 2289/4885TSHR 508/4885TDP1 4683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.