Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG7 | O95352 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.40 |
| ▸ | SRC | P12931 | 8/20 | 0.40 |
| ▸ | MTOR | P42345 | 7/20 | 0.40 |
| ▸ | KDR | P35968 | 7/20 | 0.40 |
| ▸ | ABL1 | P00519 | 6/20 | 0.40 |
| ▸ | EGFR | P00533 | 6/20 | 0.40 |
| ▸ | HCK | P08631 | 6/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 6/20 | 0.40 |
| ▸ | PRKDC | P78527 | 6/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010074 | 0.82 | ATG7 (0.52) | ATG7PIK3CDSRCMTORKDR | |
| SCHEMBL1848609 | 0.75 | ATG7 (0.43) | ATG7PIK3CDSRCMTORKDR | |
| SCHEMBL8442195 | 0.75 | SRC (0.43) | PIK3CDSRCMTORKDRABL1 | |
| SCHEMBL1847885 | 0.71 | ATG7 (0.43) | ATG7PIK3CDSRCKDRABL1 | |
| SCHEMBL2880679 | 0.68 | BTK (0.58) | PIK3CDSRCMTORKDRABL1 | |
| SCHEMBL8444992 | 0.68 | SRC (0.46) | SRCKDRABL1EGFRLCK | |
| SCHEMBL8441851 | 0.68 | DYRK3 (0.54) | SRCMTORLCKTEKDYRK1A | |
| SCHEMBL8442394 | 0.68 | SRC (0.46) | SRCLCKTEKDYRK1A | |
| SCHEMBL3779239 | 0.66 | SRC (0.55) | PIK3CDSRCMTORKDRABL1 | |
| SCHEMBL3829445 | 0.66 | ADK (0.44) | ATG7PIK3CDSRCMTORKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | US | disclosed |
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | US | disclosed |
| WO-2008049105-A2 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | HSP90AB2P, HSP90AB1, HSP90AA1 | ATG7 1635/4885PIK3CD 1789/4885SRC 131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.