Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545500 | 0.90 | SIGMAR1 (0.36) | OPRM1OPRD1SIGMAR1HRH3DRD2 | |
| SCHEMBL9034363 | 0.78 | CARM1 (0.32) | CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL3343259 | 0.78 | ADH1B (0.48) | OPRM1OPRD1SIGMAR1DRD2HTR2A | |
| SCHEMBL5789303 | 0.77 | CARM1 (0.34) | CARM1PRMT6PRMT1PRMT8HRH3 | |
| SCHEMBL82611 | 0.77 | CARM1 (0.48) | OPRM1OPRD1SIGMAR1CARM1PRMT6 | |
| SCHEMBL3343255 | 0.76 | HRH3 (0.31) | OPRM1OPRD1SIGMAR1HRH3TEAD1 | |
| SCHEMBL24243286 | 0.75 | OPRD1 (0.38) | OPRM1OPRD1SIGMAR1HRH3ADRA2A | |
| SCHEMBL4502992 | 0.75 | SIGMAR1 (0.35) | OPRM1OPRD1SIGMAR1HRH3ADRA2A | |
| SCHEMBL4959156 | 0.75 | SIGMAR1 (0.35) | OPRM1OPRD1SIGMAR1HRH3ADRA2A | |
| SCHEMBL579037 | 0.75 | SMN1; SMN2 (0.43) | CARM1PRMT6PRMT1PRMT8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | US | disclosed |
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | HSP90AB2P, HSP90AB1, HSP90AA1 | OPRM1 4593/4885OPRD1 4531/4885SIGMAR1 3342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.