SCHEMBL14201867

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19068865	0.87	CYP11B1 (0.53)	CYP11B1CYP11B2KDM1ANPC1RAB9A
	SCHEMBL17229340	0.82	CYP11B1 (0.52)	CYP11B1CYP11B2KDM1AL3MBTL1HDAC1
	SCHEMBL7563886	0.77	RAB9A (0.56)	NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E
	SCHEMBL31280939	0.77	RAB9A (0.56)	NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E
	SCHEMBL19243082	0.77	CCR1 (0.56)	CYP11B1CYP11B2KDM1ARAB9AL3MBTL1
	SCHEMBL10161953	0.76	CYP11B1 (0.60)	CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2
	SCHEMBL10161950	0.74	HDAC1 (0.49)	NPC1RAB9ASMN1; SMN2L3MBTL1HDAC1
	SCHEMBL19567242	0.74	HSD17B1 (0.47)	NPC1RAB9ASMN1; SMN2L3MBTL1TDP1
	SCHEMBL14018446	0.73	KDM1A (0.59)	CYP11B1CYP11B2KDM1ASMN1; SMN2L3MBTL1
	SCHEMBL10160852	0.72	CYP11B1 (0.56)	CYP11B1CYP11B2NPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.