Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.39 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1603395 | 0.85 | ADRB1 (0.53) | L3MBTL1ALDH1A1ADRB1SMN1; SMN2DPP4 | |
| SCHEMBL15559068 | 0.83 | ADRB1 (0.49) | ALDH1A1ADRB1SMN1; SMN2DPP4FFAR4 | |
| SCHEMBL2051137 | 0.83 | ADRB1 (0.51) | L3MBTL1ALDH1A1ADRB1SMN1; SMN2DPP4 | |
| SCHEMBL12580680 | 0.83 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1ALDH1A1MBTD1ADRB1 | |
| SCHEMBL20040866 | 0.82 | ADRB1 (0.47) | ALDH1A1ADRB1SMN1; SMN2DPP4FFAR4 | |
| SCHEMBL23113436 | 0.81 | ADRB1 (0.53) | L3MBTL1ALDH1A1ADRB1SMN1; SMN2DPP4 | |
| SCHEMBL16904561 | 0.81 | ADRB1 (0.46) | ALDH1A1ADRB1DPP4FFAR4NR2E1 | |
| SCHEMBL27508461 | 0.81 | ADRB1 (0.46) | ALDH1A1ADRB1DPP4FFAR4NR2E1 | |
| SCHEMBL1960861 | 0.81 | L3MBTL3 (0.54) | L3MBTL3L3MBTL1MBTD1FGFR1FLT1 | |
| SCHEMBL16180744 | 0.80 | L3MBTL3 (0.48) | L3MBTL3L3MBTL1ALDH1A1MBTD1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110144107-A1 | COMPOUNDS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF MALARIA | IRM LLC (BM) | 2011-06-16 | — | — | US | disclosed |
| US-20110144107-A1 | COMPOUNDS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF MALARIA | IRM LLC (BM) | 2011-06-16 | — | — | US | disclosed |
| US-20110144107-A1 | COMPOUNDS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF MALARIA | IRM LLC (BM) | 2011-06-16 | — | — | US | disclosed |
| EP-2297097-A2 | COMPOUNDS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF MALARIA | IRM LLC (BM) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009152356-A2 | COMPOUNDS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF MALARIA | IRM LLC (BM) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009152356-A2 | COMPOUNDS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF MALARIA | IRM LLC (BM) | 2009-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144107-A1 | COMPOUNDS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF MALARIA | G6PD, DHFR, SGMS1 | L3MBTL3 3831/4885L3MBTL1 3493/4885ALDH1A1 1547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.