Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 5/20 | 0.52 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.47 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10477308 | 0.78 | MMP1 (0.60) | TGM2GSTO1LMNAMEN1KMT2A | |
| SCHEMBL30452125 | 0.78 | MMP1 (0.60) | TGM2GSTO1LMNAMEN1KMT2A | |
| SCHEMBL11331053 | 0.78 | TGM2 (0.53) | TGM2GSTO1LMNAF13A1TGM1 | |
| SCHEMBL8512135 | 0.77 | MMP1 (0.58) | TGM2FGFR4GSTO1MEN1KMT2A | |
| SCHEMBL5480363 | 0.77 | TGM2 (0.50) | TGM2GSTO1LMNAKMT2AF13A1 | |
| SCHEMBL25289986 | 0.77 | MAPT (0.61) | LMNA | |
| SCHEMBL29410377 | 0.77 | MAPT (0.61) | LMNA | |
| SCHEMBL3419678 | 0.76 | NPSR1 (0.59) | TYK2LMNAMEN1KMT2APDK1 | |
| SCHEMBL4732340 | 0.76 | ALDH1A1 (0.62) | TGM2GSTO1LMNAKMT2AF13A1 | |
| SCHEMBL9493239 | 0.76 | EPHB4 (0.53) | TGM2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053158-A1 | INHIBITORS OF P38 MITOGEN-ACTIVATED PROTEIN KINASE | CHROMA THERAPEUTICS LTD. (GB) | 2008-05-08 | — | — | WO | disclosed |