Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB2 | O60825 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.46 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.46 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10096731 | 0.93 | PFKFB2 (0.46) | PFKFB2NSD2PFKFB1PFKFB3DOT1L | |
| SCHEMBL10095947 | 0.91 | MTNR1B (0.49) | PFKFB2NSD2PFKFB1PFKFB3DOT1L | |
| SCHEMBL10096733 | 0.90 | NPY5R (0.46) | PFKFB2NSD2PFKFB1PFKFB3DOT1L | |
| SCHEMBL10096734 | 0.90 | KMT2A (0.49) | PFKFB2NSD2PFKFB1PFKFB3DOT1L | |
| SCHEMBL4793520 | 0.89 | ALDH1A1 (0.50) | PFKFB2NSD2PFKFB1PFKFB3DOT1L | |
| SCHEMBL4793515 | 0.89 | PFKFB2 (0.42) | PFKFB2NSD2PFKFB1PFKFB3DOT1L | |
| SCHEMBL10096736 | 0.88 | RAB9A (0.55) | PFKFB2NSD2PFKFB1PFKFB3DOT1L | |
| SCHEMBL10096239 | 0.88 | MAPK1 (0.42) | PFKFB2NSD2PFKFB1PFKFB3DOT1L | |
| SCHEMBL12109376 | 0.88 | PFKFB2 (0.41) | PFKFB2NSD2PFKFB1PFKFB3DOT1L | |
| SCHEMBL10096735 | 0.88 | MAPT (0.42) | PFKFB2NSD2PFKFB1PFKFB3DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096928-A9 | Indole compounds that modify translational control of Hepatitis C virus | PTC THERAPEUTICS, INC. | 2008-04-24 | — | — | US | disclosed |
| US-20080096928-A9 | Indole compounds that modify translational control of Hepatitis C virus | PTC THERAPEUTICS, INC. | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096928-A9 | Indole compounds that modify translational control of Hepatitis C virus | EIF2AK2, INMT, IDO1 | PFKFB2 3890/4885NSD2 1103/4885PFKFB1 3870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.