Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | NSD2 | O96028 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL29551365 | 1.00 | MAPT (0.41) | MAPTKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL2271462 | 0.92 | KDM4E (0.46) | MAPTKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL29496561 | 0.92 | KDM4E (0.46) | MAPTKDM4EALDH1A1KMT2AHPGD | |
| Bromide SCHEMBL9694606 | 0.90 | MAPT (0.48) | MAPTKDM4EALDH1A1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL7776252 | 0.90 | KDM4E (0.44) | MAPTKDM4EALDH1A1KMT2AHPGD | |
| Iodide SCHEMBL2234372 | 0.90 | KDM4E (0.44) | MAPTKDM4EALDH1A1KMT2AHPGD | |
| Iodide SCHEMBL6093239 | 0.90 | KDM4E (0.44) | MAPTKDM4EALDH1A1KMT2AHPGD | |
| Iodide SCHEMBL29496722 | 0.90 | KDM4E (0.44) | MAPTKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL22320975 | 0.84 | KDM4E (0.41) | MAPTKDM4EALDH1A1KMT2AHPGD | |
| SCHEMBL6754886 | 0.84 | KDM4E (0.41) | MAPTKDM4EALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906354-B2 | Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes | BRUKER BIOSPIN CORPORATION (US) | 2014-12-09 | — | — | US | disclosed |
| US-8841134-B2 | Fluorescence resonance energy transfer detection with nanoparticles for in vitro and in vivo applications | BRUKER BIOSPIN CORPORATION (US) | 2014-09-23 | — | — | US | disclosed |
| US-20120058050-A1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES | BRUKER BIOSPIN CORPORATION | 2012-03-08 | — | — | US | disclosed |
| EP-2004713-B1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES | CARESTREAM HEALTH INC (US) | 2011-03-09 | — | — | EP | disclosed |
| US-20100034748-A1 | Molecular imaging probes based on loaded reactive nano-scale latex | QUANTUM MEDICAL HOLDINGS, LLC | 2010-02-11 | — | — | US | disclosed |
| US-20090061532-A1 | FLUORESCENCE RESONANCE ENERGY TRANSFER DETECTION WITH NANOPARTICLES FOR IN VITRO AND IN VIVO APPLICATIONS | CARESTREAM HEALTH, INC. | 2009-03-05 | — | — | US | disclosed |
| US-20080181965-A1 | Loaded latex optical molecular imaging probes | QUANTUM MEDICAL HOLDINGS, LLC | 2008-07-31 | — | — | US | disclosed |
| US-4151162-A | Diazomerocyanines and mesomeric forms thereof | L'OREAL (FR) | 1979-04-24 | — | — | US | disclosed |
| US-3985499-A | Diazamerocyanines for dyeing keratinous fibers | L'OREAL (FR) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080181965-A1 | Loaded latex optical molecular imaging probes | MLX, LOXL1, EPX | MAPT 2883/4885KDM4E 1078/4885ALDH1A1 2212/4885 |
| US-20100034748-A1 | Molecular imaging probes based on loaded reactive nano-scale latex | CLTA, COPE, CD68 | MAPT 722/4885KDM4E 3184/4885ALDH1A1 2203/4885 |
| US-20120058050-A1 | LOADED LATEX OPTICAL MOLECULAR IMAGING PROBES CONTAINING LIPOPHILIC LARGE STOKES SHIFT DYES | LASP1, LSS, SELL | MAPT 1897/4885KDM4E 1542/4885ALDH1A1 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.