Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210544 | 0.91 | ALDH1A1 (0.46) | THRBTHRAHRH3TSHRKDM4E | |
| SCHEMBL12132510 | 0.88 | HRH3 (0.49) | THRBTHRAHRH3DRD3TSHR | |
| SCHEMBL12132513 | 0.79 | KMT2A (0.55) | THRBTHRAHRH3TSHRKDM4E | |
| SCHEMBL12132512 | 0.77 | ATM (0.57) | THRBTHRAKDM4EALDH1A1MAPT | |
| SCHEMBL13485578 | 0.72 | TP53 (0.47) | THRBTHRAHRH3KDM4EALDH1A1 | |
| SCHEMBL12132530 | 0.72 | KMT2A (0.58) | HRH3DRD3TSHRKDM4EALDH1A1 | |
| SCHEMBL13601498 | 0.71 | DNM1 (0.49) | THRBTHRAALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL822424 | 0.71 | THRB (0.47) | THRBTHRAHRH3KDM4EALDH1A1 | |
| SCHEMBL14201122 | 0.71 | THRB (0.44) | THRBTSHRKDM4EALDH1A1MAPT | |
| SCHEMBL673537 | 0.70 | ALDH1A1 (0.44) | THRBTHRATSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008061954-A1 | NOVEL CO-INITIATORS | AGFA GRAPHICS NV (BE) | 2008-05-29 | — | — | WO | disclosed |