Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14207676 | 0.88 | HDAC4 (0.38) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL10331383 | 0.88 | HDAC4 (0.40) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL754423 | 0.88 | HDAC4 (0.40) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL10331384 | 0.88 | HDAC4 (0.40) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL764322 | 0.85 | NR3C1 (0.37) | CES2CES1 | |
| SCHEMBL10201035 | 0.78 | KCNQ2 (0.39) | DPP4DPP7OPRM1 | |
| SCHEMBL753423 | 0.77 | AR (0.40) | MEN1KMT2AMTORKDM4EDPP4 | |
| SCHEMBL753573 | 0.76 | HDAC4 (0.41) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL14207655 | 0.74 | CES2 (0.41) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL10331380 | 0.72 | NR3C1 (0.37) | HDAC4CES2CES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057859-A2 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-I AND/OR NF-KAPPAB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-15 | — | — | WO | disclosed |