SCHEMBL14208584

SCHEMBL14208584

CO[C@H]1OC(COS(=O)(=O)O)C[C@H](O[C@@H]2OC(C(=O)O)[C@@H](O)[C@H](O)C2O)C1C

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 5/20 0.39
▸ BDNF P23560 3/20 0.37
▸ PTN P21246 2/20 0.37
▸ MDK P21741 2/20 0.37
▸ SERPINC1 P01008 1/20 0.35
▸ FGF2 P09038 1/20 0.35
▸ ABCC1 P33527 1/20 0.32
▸ M6PR P20645 1/20 0.31
▸ AKT1 P31749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14208603 0.89 BDNF (0.38) F10BDNFPTNMDKSERPINC1
SCHEMBL14208602 0.89 BDNF (0.38) F10BDNFPTNMDKSERPINC1
SCHEMBL14208595 0.85 FGF2 (0.39) FGF2AKT1
SCHEMBL14208598 0.82 — —
SCHEMBL14208599 0.80 BDNF (0.47) F10BDNFPTNMDKFGF2
SCHEMBL14208664 0.79 F10 (0.51) F10BDNFPTNMDKSERPINC1
SCHEMBL14765307 0.73 FGF2 (0.40) FGF2AKT1
SCHEMBL14208633 0.73 FGF2 (0.40) FGF2AKT1
SCHEMBL14208645 0.73 FGF2 (0.40) FGF2AKT1
SCHEMBL14208600 0.73 BDNF (0.51) F10BDNFPTNMDKSERPINC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785416-B2 Sulphated disaccharides for the treatment of neurodegenerative and/or neurovascular diseases BIOIBERICA, S.A. (ES) 2014-07-22 — — US disclosed
US-20120309707-A1 SULPHATED DISACCHARIDES FOR THE TREATMENT OF NEURODEGENERATIVE AND/OR NEUROVASCULAR DISEASES UNIVERSIDAD AUTONOMA DE MADRID (ES) 2012-12-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309707-A1 SULPHATED DISACCHARIDES FOR THE TREATMENT OF NEURODEGENERATIVE AND/OR NEUROVASCULAR DISEASES GALC, SMN1; SMN2, SORD F10 718/4885BDNF 46/4885PTN 1620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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