SCHEMBL14208595

SCHEMBL14208595

CO[C@H]1OC(CO)C[C@H](O[C@@H]2OC(C(=O)O)[C@@H](O)[C@H](O)C2O)C1C

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ FGF2 P09038 1/20 0.39
▸ MAPT P10636 1/20 0.34
▸ STAT3 P40763 7/20 0.34
▸ AKT1 P31749 1/20 0.33
▸ SYNJ2 O15056 1/20 0.32
▸ VDR P11473 1/20 0.32
▸ SELE P16581 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ GLA P06280 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ DRD2 P14416 1/20 0.31
▸ DRD1 P21728 1/20 0.31
▸ ABCC4 O15439 1/20 0.31
▸ CYP2C8 P10632 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14208645 0.88 FGF2 (0.40) FGF2MAPTSTAT3AKT1SYNJ2
SCHEMBL14208633 0.88 FGF2 (0.40) FGF2MAPTSTAT3AKT1SYNJ2
SCHEMBL14765307 0.88 FGF2 (0.40) FGF2MAPTSTAT3AKT1SYNJ2
SCHEMBL14208584 0.85 F10 (0.39) FGF2AKT1
SCHEMBL25445500 0.73 FGF2 (0.38) FGF2MAPTKDM4EALDH1A1GLA
SCHEMBL14208603 0.73 BDNF (0.38) FGF2AKT1VDRKDM4EALDH1A1
SCHEMBL14208602 0.73 BDNF (0.38) FGF2AKT1VDRKDM4EALDH1A1
SCHEMBL8267592 0.73 FGF2 (0.37) FGF2AKT1KDM4EALDH1A1GLA
SCHEMBL13814803 0.73 FGF2 (0.37) FGF2AKT1KDM4EALDH1A1GLA
SCHEMBL18372818 0.73 FGF2 (0.37) FGF2AKT1KDM4EALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785416-B2 Sulphated disaccharides for the treatment of neurodegenerative and/or neurovascular diseases BIOIBERICA, S.A. (ES) 2014-07-22 — — US disclosed
US-20120309707-A1 SULPHATED DISACCHARIDES FOR THE TREATMENT OF NEURODEGENERATIVE AND/OR NEUROVASCULAR DISEASES UNIVERSIDAD AUTONOMA DE MADRID (ES) 2012-12-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309707-A1 SULPHATED DISACCHARIDES FOR THE TREATMENT OF NEURODEGENERATIVE AND/OR NEUROVASCULAR DISEASES GALC, SMN1; SMN2, SORD FGF2 358/4885MAPT 12/4885STAT3 2541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback