SCHEMBL14765307

SCHEMBL14765307

CC1[C@@H](O[C@@H]2OC(C(=O)O)[C@@H](O)[C@H](O)C2O)CC(CO)O[C@@H]1C

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ FGF2 P09038 1/20 0.40
▸ MAPT P10636 1/20 0.35
▸ SELE P16581 3/20 0.35
▸ STAT3 P40763 5/20 0.35
▸ AKT1 P31749 1/20 0.34
▸ DRD2 P14416 2/20 0.34
▸ DRD1 P21728 2/20 0.34
▸ SYNJ2 O15056 1/20 0.33
▸ VDR P11473 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ GLA P06280 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ IDUA P35475 1/20 0.32
▸ ABCC4 O15439 1/20 0.32
▸ CYP2C8 P10632 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14208645 1.00 FGF2 (0.40) FGF2MAPTSELESTAT3AKT1
SCHEMBL14208633 1.00 FGF2 (0.40) FGF2MAPTSELESTAT3AKT1
SCHEMBL14208595 0.88 FGF2 (0.39) FGF2MAPTSELESTAT3AKT1
SCHEMBL14208602 0.84 BDNF (0.38) FGF2AKT1DRD2DRD1VDR
SCHEMBL14208603 0.84 BDNF (0.38) FGF2AKT1DRD2DRD1VDR
SCHEMBL25445500 0.75 FGF2 (0.38) FGF2MAPTDRD2DRD1KDM4E
SCHEMBL18079538 0.74 MDK (0.36) STAT3MAPK1
SCHEMBL25445487 0.74 MDK (0.36) STAT3MAPK1
SCHEMBL14208584 0.73 F10 (0.39) FGF2AKT1
SCHEMBL18412621 0.70 SELE (0.43) FGF2SELESTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785416-B2 Sulphated disaccharides for the treatment of neurodegenerative and/or neurovascular diseases BIOIBERICA, S.A. (ES) 2014-07-22 — — US disclosed
US-8394781-B2 Disaccharides for the treatment of tendons, ligaments, and bones BIOIBERICA, S.A. (ES) 2013-03-12 — — US disclosed
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