Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | PLAU | P00749 | 5/20 | 0.44 |
| ▸ | HPN | P05981 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284482 | 1.00 | MMP2 (0.53) | MMP2MMP9PLAUHPNTDP1 | |
| SCHEMBL1115907 | 0.87 | MMP2 (0.56) | MMP2MMP9PLAUHPNTDP1 | |
| SCHEMBL284484 | 0.87 | MMP2 (0.56) | MMP2MMP9PLAUHPNTDP1 | |
| SCHEMBL6571626 | 0.84 | MMP9 (0.65) | MMP2MMP9PLAUHPNTDP1 | |
| SCHEMBL796114 | 0.84 | MMP9 (0.65) | MMP2MMP9PLAUHPNTDP1 | |
| SCHEMBL5470148 | 0.83 | MMP2 (0.57) | MMP2MMP9PLAUHPNTDP1 | |
| SCHEMBL5470145 | 0.83 | MMP2 (0.57) | MMP2MMP9PLAUHPNTDP1 | |
| Hydrochloric Acid SCHEMBL14059215 | 0.83 | MMP9 (0.64) | MMP2MMP9PLAUHPNTDP1 | |
| SCHEMBL28509074 | 0.83 | MMP2 (0.60) | MMP2MMP9PLAUHPNTDP1 | |
| SCHEMBL8965842 | 0.82 | MMP9 (0.65) | MMP2MMP9PLAUHPNTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086005-A1 | MODULATING INTERSTITIAL PRESSURE AND ONCOLYTIC VIRAL DELIVERY AND DISTRIBUTION | ONCOLYTICS BIOTECH INC. (CA) | 2011-04-14 | — | — | US | claimed |
| EP-1708677-A2 | COSMETIC COMPOSITION CONTAINING A PROTEIN AND AN ENZYME INHIBITOR | E-L Management Corp. (US) | 2006-10-11 | — | — | EP | claimed |
| WO-2005067691-A2 | COSMETIC COMPOSITION CONTAINING A PROTEIN AND AN ENZYME INHIBITOR | E-L MANAGEMENT CORPORATION (US) | 2005-07-28 | — | — | WO | claimed |
| US-20050147572-A1 | Cosmetic composition containing a protein and an enzyme inhibitor | E-L MANAGEMENT CORP. | 2005-07-07 | — | — | US | claimed |
| EP-0230670-B1 | NOVEL HOST E. COLI AND USE THEREOF | SUNTORY LIMITED (JP) | 1991-07-03 | — | — | EP | claimed |
| WO-2024151802-A2 | METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING ITCH | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-07-18 | — | — | WO | disclosed |
| US-20240158513-A1 | FC Variants and Methods for Their Production | GENENTECH, INC. (US) | 2024-05-16 | — | — | US | disclosed |
| US-10689447-B2 | Fc variants and methods for their production | GENENTECH, INC. (US) | 2020-06-23 | — | — | US | disclosed |
| EP-2670776-B1 | Fc VARIANTS AND METHODS FOR THEIR PRODUCTION | HOFFMANN LA ROCHE (CH) | 2018-11-21 | — | — | EP | disclosed |
| WO-2018055235-A1 | ISOXAZOLE-AMIDES FOR TREATING CARDIAC DISEASES | UNIVERSITY OF HELSINKI (FI) | 2018-03-29 | — | — | WO | disclosed |
| US-9841423-B2 | Methods for diagnosing and treating Helicobacter pylori infection | NATIONAL TSING HUA UNIVERSITY (TW) | 2017-12-12 | — | — | US | disclosed |
| US-20170082621-A1 | METHODS FOR DIAGNOSING AND TREATING HELICOBACTER PYLORI INFECTION | NATIONAL TSING HUA UNIVERSITY (TW) | 2017-03-23 | — | — | US | disclosed |
| EP-1708677-A2 | COSMETIC COMPOSITION CONTAINING A PROTEIN AND AN ENZYME INHIBITOR | E-L Management Corp. (US) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005067691-A2 | COSMETIC COMPOSITION CONTAINING A PROTEIN AND AN ENZYME INHIBITOR | E-L MANAGEMENT CORPORATION (US) | 2005-07-28 | — | — | WO | disclosed |
| US-20050147572-A1 | Cosmetic composition containing a protein and an enzyme inhibitor | E-L MANAGEMENT CORP. | 2005-07-07 | — | — | US | disclosed |
| US-6331610-B1 | TREATING VIRAL DISEASES IN HUMAN CELLS AND TISSUES; ADMINISTER VIRICIDES, MONITOR CELLS FOR VIRAL EXPRESSION | METATRON, INC. | 2001-12-18 | — | — | US | disclosed |
| WO-2000052034-A2 | INHIBITORS OF SERINE PROTEASE ACTIVITY, METHODS AND COMPOSITIONS FOR TREATMENT OF VIRAL INFECTIONS | THE TRUSTEES OF UNIVERSITY TECHNOLOGY CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |
| EP-0360840-A1 | CYTOLYTIC FACTOR | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1990-04-04 | — | — | EP | disclosed |
| WO-1988007868-A1 | CYTOLYTIC FACTOR | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1988-10-20 | — | — | WO | disclosed |
| WO-1988000236-A1 | METHODS AND MATERIALS FOR VANADIUM IMMUNOMODULATION | TOMPKINS WAYNE A F (US) | 1988-01-14 | — | — | WO | disclosed |