Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.59 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.59 |
| ▸ | GRK6 | P43250 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | FABP4 | P15090 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1421138 | 1.00 | MEN1 (0.61) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL1421482 | 0.89 | FAAH (0.73) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL1421478 | 0.89 | FAAH (0.73) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL12726855 | 0.85 | MEN1 (0.70) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL1421441 | 0.85 | KMT2A (0.81) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL1421437 | 0.85 | KMT2A (0.81) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL1421134 | 0.85 | MEN1 (0.61) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL1421130 | 0.85 | MEN1 (0.61) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL1421133 | 0.85 | MEN1 (0.61) | MEN1KMT2AMAPTCACNA1BAPBA1 | |
| SCHEMBL1421490 | 0.85 | MEN1 (0.68) | MEN1KMT2AMAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098323-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | MICROBIOTIX, INC. (US) | 2011-04-28 | — | — | US | disclosed |
| US-20110098323-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | MICROBIOTIX, INC. (US) | 2011-04-28 | — | — | US | disclosed |
| US-20110098323-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | MICROBIOTIX, INC. (US) | 2011-04-28 | — | — | US | disclosed |
| EP-2296476-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | Microbiotix, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009142720-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | MICROBIOTIX, INC. (US) | 2009-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098323-A1 | INHIBITORS OF BACTERIAL BIOFILM FORMATION | BLVRB, TFPI, FOSB | MEN1 4836/4885KMT2A 3896/4885MAPT 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.