Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25164620 | 0.85 | RXRA (0.38) | ARRXRAGRIN1GRIN2BFFAR4 | |
| SCHEMBL20288406 | 0.79 | MBOAT4 (0.45) | ARASPHCTSSCTSK | |
| SCHEMBL10233515 | 0.77 | GPBAR1 (0.39) | ARRXRAGRIN1GRIN2BALDH1A1 | |
| SCHEMBL21010496 | 0.77 | AR (0.37) | ARRXRAGRIN1GRIN2BASPH | |
| SCHEMBL12329889 | 0.76 | NOTUM (0.36) | ARALDH1A1CTSSCTSK | |
| SCHEMBL19485462 | 0.76 | MBOAT4 (0.45) | ARGPBAR1 | |
| SCHEMBL12828161 | 0.74 | CYP11B2 (0.39) | CYP11B2CYP11B1KIF11ASPH | |
| SCHEMBL25994122 | 0.72 | AR (0.62) | AR | |
| SCHEMBL20772336 | 0.69 | PIK3CD (0.42) | KIF11ASPH | |
| SCHEMBL10272611 | 0.69 | NOS3 (0.35) | RXRAGRIN1GRIN2BGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |