Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9863737 | 0.78 | — | — | |
| SCHEMBL28935092 | 0.74 | ALDH1A1 (0.36) | TRPA1ALDH1A1MAPK1 | |
| SCHEMBL28124242 | 0.74 | FPR2 (0.56) | GAPDHFPR2ALDH1A1CMKLR1ACHE | |
| SCHEMBL11041657 | 0.73 | — | — | |
| SCHEMBL13316122 | 0.73 | — | — | |
| SCHEMBL3805343 | 0.73 | — | — | |
| SCHEMBL7940124 | 0.73 | ACHE (0.40) | GAPDHTRPA1DDAH1MAPTFPR2 | |
| SCHEMBL14303487 | 0.72 | CMKLR1 (0.57) | GAPDHFPR2ALDH1A1CMKLR1LTB4R | |
| SCHEMBL13077313 | 0.71 | — | — | |
| SCHEMBL6535459 | 0.71 | ALDH1A1 (0.37) | GAPDHTRPA1DDAH1MAPTFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108694-A1 | Novel Macrocycles and Uses Thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108694-A1 | Novel Macrocycles and Uses Thereof | BDKRB1, RPS4Y1, GRK4 | GAPDH 4233/4885TRPA1 4657/4885DDAH1 2552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.